| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | lpdA | SO_0425 | SO_0426 | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Dihydrolipoamide dehydrogenase LpdA. | 0.999 |
| aceF | nuoCD | SO_0425 | SO_1019 | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | NADH-ubiquinone oxidoreductase subunit CD NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.825 |
| aceF | sdhC | SO_0425 | SO_1927 | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase cytochrome b556 subunit SdhC. | 0.603 |
| aceF | sdhD | SO_0425 | SO_4778 | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Succinate dehydrogenase membrane anchor subunit SdhD; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.538 |
| aceF | sucA | SO_0425 | SO_1930 | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 2-oxoglutarate dehydrogenase complex dehydrogenase E1 component SucA. | 0.992 |
| aceF | sucC | SO_0425 | SO_1932 | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthase beta subunit SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.971 |
| aceF | sucD | SO_0425 | SO_1933 | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | succinyl-CoA synthase alpha subunit SucD; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.963 |
| bkdB | lpdA | SO_2341 | SO_0426 | 3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB. | Dihydrolipoamide dehydrogenase LpdA. | 0.997 |
| bkdB | nuoCD | SO_2341 | SO_1019 | 3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB. | NADH-ubiquinone oxidoreductase subunit CD NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.785 |
| bkdB | sdhC | SO_2341 | SO_1927 | 3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB. | Succinate dehydrogenase cytochrome b556 subunit SdhC. | 0.433 |
| bkdB | sucA | SO_2341 | SO_1930 | 3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB. | 2-oxoglutarate dehydrogenase complex dehydrogenase E1 component SucA. | 0.984 |
| bkdB | sucC | SO_2341 | SO_1932 | 3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB. | succinyl-CoA synthase beta subunit SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.766 |
| bkdB | sucD | SO_2341 | SO_1933 | 3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB. | succinyl-CoA synthase alpha subunit SucD; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.698 |
| icd | sucA | SO_2629 | SO_1930 | Isocitrate dehydrogenase NADP-dependent Icd; Belongs to the monomeric-type IDH family. | 2-oxoglutarate dehydrogenase complex dehydrogenase E1 component SucA. | 0.926 |
| icd | sucC | SO_2629 | SO_1932 | Isocitrate dehydrogenase NADP-dependent Icd; Belongs to the monomeric-type IDH family. | succinyl-CoA synthase beta subunit SucC; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.561 |
| icd | sucD | SO_2629 | SO_1933 | Isocitrate dehydrogenase NADP-dependent Icd; Belongs to the monomeric-type IDH family. | succinyl-CoA synthase alpha subunit SucD; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.548 |
| lpdA | aceF | SO_0426 | SO_0425 | Dihydrolipoamide dehydrogenase LpdA. | Dihydrolipoamide acetyltransferase AceF; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
| lpdA | bkdB | SO_0426 | SO_2341 | Dihydrolipoamide dehydrogenase LpdA. | 3-methyl-2-oxobutanoate dehydrogenase complex E2 component BkdB. | 0.997 |
| lpdA | nuoCD | SO_0426 | SO_1019 | Dihydrolipoamide dehydrogenase LpdA. | NADH-ubiquinone oxidoreductase subunit CD NuoCD; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.772 |
| lpdA | sdhC | SO_0426 | SO_1927 | Dihydrolipoamide dehydrogenase LpdA. | Succinate dehydrogenase cytochrome b556 subunit SdhC. | 0.655 |
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