| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_3442 | cobB | SO_3442 | SO_1938 | Nucleoside triphosphate pyrophosphohydrolase. | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | 0.901 |
| SO_3442 | nadD | SO_3442 | SO_1171 | Nucleoside triphosphate pyrophosphohydrolase. | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.903 |
| SO_3442 | nadE | SO_3442 | SO_2021 | Nucleoside triphosphate pyrophosphohydrolase. | NH(3)-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.900 |
| SO_3442 | nadF | SO_3442 | SO_1523 | Nucleoside triphosphate pyrophosphohydrolase. | NAD kinase NadF; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.901 |
| SO_3442 | nadV | SO_3442 | SO_1981 | Nucleoside triphosphate pyrophosphohydrolase. | Nicotinamide phosphoribosyltransferase NadV; Belongs to the NAPRTase family. | 0.913 |
| SO_3442 | pntA | SO_3442 | SO_3740 | Nucleoside triphosphate pyrophosphohydrolase. | NAD(P) transhydrogenase alpha subunit PntA; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.900 |
| SO_3442 | pntB | SO_3442 | SO_3741 | Nucleoside triphosphate pyrophosphohydrolase. | NAD(P) transhydrogenase beta subunit PntB; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.902 |
| cobB | SO_3442 | SO_1938 | SO_3442 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Nucleoside triphosphate pyrophosphohydrolase. | 0.901 |
| cobB | deoD | SO_1938 | SO_0092 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Purine nucleoside phosphorylase DeoD. | 0.910 |
| cobB | deoD-2 | SO_1938 | SO_1221 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Purine nucleoside phosphorylase DeoD. | 0.910 |
| cobB | deoD-3 | SO_1938 | SO_2719 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Purine nucleoside phosphorylase DeoD. | 0.910 |
| cobB | nadD | SO_1938 | SO_1171 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.938 |
| cobB | nadE | SO_1938 | SO_2021 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NH(3)-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.934 |
| cobB | nadF | SO_1938 | SO_1523 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NAD kinase NadF; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.937 |
| cobB | nadV | SO_1938 | SO_1981 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | Nicotinamide phosphoribosyltransferase NadV; Belongs to the NAPRTase family. | 0.931 |
| cobB | pntA | SO_1938 | SO_3740 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NAD(P) transhydrogenase alpha subunit PntA; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. | 0.909 |
| cobB | pntB | SO_1938 | SO_3741 | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | NAD(P) transhydrogenase beta subunit PntB; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.901 |
| deoD | cobB | SO_0092 | SO_1938 | Purine nucleoside phosphorylase DeoD. | Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. | 0.910 |
| deoD | deoD-2 | SO_0092 | SO_1221 | Purine nucleoside phosphorylase DeoD. | Purine nucleoside phosphorylase DeoD. | 0.903 |
| deoD | deoD-3 | SO_0092 | SO_2719 | Purine nucleoside phosphorylase DeoD. | Purine nucleoside phosphorylase DeoD. | 0.905 |