STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SO_1986RNA polymerase sigma factor ECF family 11; Belongs to the sigma-70 factor family. ECF subfamily. (198 aa)    
Predicted Functional Partners:
chrR
anti-ECFsigma factor ChrR.
 
 
 0.990
rseA
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
  
 
 0.920
SO_3096
RNA polymerase sigma factor ECF family 28; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.920
SO_3551
RNA polymerase sigma-70 factor ECF subfamily.
  
  
 0.912
SO_1987
ATP-dependent protease La (LON) domain protein.
 
   
 0.880
rseB
Sigma E factor regulatory protein RseB.
  
 
 0.806
cfaS
Cyclopropane-fatty-acyl-phospholipid synthase CfaS.
 
  
 0.793
SO_4169
Deoxyribodipyrimidine photolyase-related protein.
  
   
 0.791
SO_4170
Cell-cell signaling protein C-factor.
  
   
 0.766
SO_3386
Bifunctional protein of unknown functions DUF523 and DUF1722.
  
  
 0.765
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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