Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
frmAS-(hydroxymethyl)glutathione dehydrogenase FrmA; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (379 aa)    
Predicted Functional Partners:
frmB
S-formylglutathione hydrolase FrmB; Serine hydrolase involved in the detoxification of formaldehyde.
 0.999
adhE
Aldehyde-alcohol dehydrogenase AdhE; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.997
adhB
Alcohol dehydrogenase II AdhB.
    
 0.969
aqpZ
Aquaporin Z AqpZ; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
 
 0.963
exaC
NAD+-dependent acetaldehyde dehydrogenase ExaC; Belongs to the aldehyde dehydrogenase family.
  
 0.920
thiG
Thiazole-phosphate synthase ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
      
 0.759
argG
Argininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
 
    
 0.728
kdnB
Alcohol dehydrogenase iron-containing; Catalyzes the first step of the biosynthesis of Kdo8N (8- amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate).
    
 
 0.703
gfaA
Glutathione-dependent formaldehyde-activating enzyme GfaA.
  
 
 0.584
gfaB
Glutathione-dependent formaldehyde-activating enzyme GfaB.
  
 
 0.563
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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