| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_3047 | tyrP | SO_3047 | SO_2065 | Protein of unknown function DUF1097. | Tyrosine transporter TyrP. | 0.685 |
| SO_3047 | yecM | SO_3047 | SO_2182 | Protein of unknown function DUF1097. | Protein of unknown function YecM. | 0.751 |
| aroG | trpCF | SO_0756 | SO_3022 | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. | 0.629 |
| aroG | tyrA | SO_0756 | SO_1362 | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. | 0.639 |
| aroG | tyrP | SO_0756 | SO_2065 | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Tyrosine transporter TyrP. | 0.490 |
| aroG | tyrR | SO_0756 | SO_1669 | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | Sigma54-dependent transcriptional activator of amino acid degradation TyrR. | 0.801 |
| brnQ | tyrP | SO_0949 | SO_2065 | Branched-chain amino acid: cation symporter BrnQ; Component of the transport system for branched-chain amino acids. | Tyrosine transporter TyrP. | 0.529 |
| brnQ | tyrR | SO_0949 | SO_1669 | Branched-chain amino acid: cation symporter BrnQ; Component of the transport system for branched-chain amino acids. | Sigma54-dependent transcriptional activator of amino acid degradation TyrR. | 0.492 |
| folA | tyrA | SO_3646 | SO_1362 | Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. | 0.524 |
| folA | tyrP | SO_3646 | SO_2065 | Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Tyrosine transporter TyrP. | 0.477 |
| folA | tyrR | SO_3646 | SO_1669 | Dihydrofolate reductase FolA; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | Sigma54-dependent transcriptional activator of amino acid degradation TyrR. | 0.689 |
| sdaC | trpR | SO_0919 | SO_3419 | Serine uptake transporter SdaC. | Transcriptional repressor of aromatic amino acid biosynthesis TrpR. | 0.443 |
| sdaC | tyrP | SO_0919 | SO_2065 | Serine uptake transporter SdaC. | Tyrosine transporter TyrP. | 0.522 |
| trpCF | aroG | SO_3022 | SO_0756 | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. | Phospho-2-dehydro-3-deoxyheptonate aldolase phe-sensitive AroG; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.629 |
| trpCF | trpR | SO_3022 | SO_3419 | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. | Transcriptional repressor of aromatic amino acid biosynthesis TrpR. | 0.771 |
| trpCF | tyrA | SO_3022 | SO_1362 | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. | 0.882 |
| trpCF | tyrP | SO_3022 | SO_2065 | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. | Tyrosine transporter TyrP. | 0.463 |
| trpR | sdaC | SO_3419 | SO_0919 | Transcriptional repressor of aromatic amino acid biosynthesis TrpR. | Serine uptake transporter SdaC. | 0.443 |
| trpR | trpCF | SO_3419 | SO_3022 | Transcriptional repressor of aromatic amino acid biosynthesis TrpR. | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. | 0.771 |
| trpR | tyrA | SO_3419 | SO_1362 | Transcriptional repressor of aromatic amino acid biosynthesis TrpR. | Bifunctional chorismate mutase T/prephenate dehydrogenase TyrA. | 0.511 |