STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hyaBPeriplasmic [Ni-Fe] hydrogenase large subunit HyaB; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)    
Predicted Functional Partners:
hyaA
Periplasmic [Ni-Fe] hydrogenase small subunit HyaA.
 
 
 0.999
hyaC
Periplasmic [Ni-Fe] hydrogenase cytochrome b subunit HyaC.
 
 
 0.998
hypA
NiFe hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.975
hyaD
NiFe hydrogenase maturation protease HyaD.
 
 
 0.974
hypF
NiFe hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide.
 
 
 
 0.951
hypC
NiFe hydrogenase assembly chaperone HypC.
 
 
 0.916
hypD
NiFe hydrogenase expression/formation protein HypD; Belongs to the HypD family.
 
 
 0.910
hypB
Ni2+-binding GTPase involved in regulation of NiFe hydrogenase expression and maturation HypB.
 
  
 0.892
hypE
NiFe hydrogenase accessory/formation protein HypE.
 
   
 0.880
hyaE
NiFe hydrogenase assembly chaperone HyaE.
  
 
 0.769
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.