| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0622 | SO_0859 | SO_0622 | SO_0859 | Two component signal transduction system response regulator. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.939 |
| SO_0622 | SO_4002 | SO_0622 | SO_4002 | Two component signal transduction system response regulator. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.863 |
| SO_0622 | barA | SO_0622 | SO_3457 | Two component signal transduction system response regulator. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.876 |
| SO_0622 | qseC | SO_0622 | SO_2105 | Two component signal transduction system response regulator. | AI-3-responsive two component signal transduction system histidine kinase QseC. | 0.854 |
| SO_0859 | SO_0622 | SO_0859 | SO_0622 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator. | 0.939 |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.991 |
| SO_0859 | cpxR | SO_0859 | SO_4477 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Periplasmic stress-responsive two component signal transduction system response regulator CpxR. | 0.935 |
| SO_0859 | kdpE | SO_0859 | SO_0059 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two-component system, OmpR family, KDP operon response regulator KdpE; Two component signal transduction system controlling the osmosenstive K+ channel response regulator KdpE. | 0.927 |
| SO_0859 | phoB | SO_0859 | SO_1558 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Phosphate-responsive two component signal transduction system response regulator PhoB. | 0.933 |
| SO_0859 | phoP | SO_0859 | SO_1946 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator PhoP. | 0.939 |
| SO_0859 | qseB | SO_0859 | SO_2104 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | AI-3-responsive two component signal transduction system response regulator QseB. | 0.927 |
| SO_0859 | qseC | SO_0859 | SO_2105 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | AI-3-responsive two component signal transduction system histidine kinase QseC. | 0.877 |
| SO_0859 | rstA | SO_0859 | SO_3594 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system controlling curli production response regulator RstA. | 0.932 |
| SO_4002 | SO_0622 | SO_4002 | SO_0622 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator. | 0.863 |
| SO_4002 | SO_0859 | SO_4002 | SO_0859 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.991 |
| SO_4002 | barA | SO_4002 | SO_3457 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.991 |
| SO_4002 | cpxR | SO_4002 | SO_4477 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Periplasmic stress-responsive two component signal transduction system response regulator CpxR. | 0.869 |
| SO_4002 | kdpE | SO_4002 | SO_0059 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two-component system, OmpR family, KDP operon response regulator KdpE; Two component signal transduction system controlling the osmosenstive K+ channel response regulator KdpE. | 0.877 |
| SO_4002 | phoB | SO_4002 | SO_1558 | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Phosphate-responsive two component signal transduction system response regulator PhoB. | 0.866 |