| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_2914 | ndpA | SO_2914 | SO_2177 | Protein of unknown function DUF412. | Nucleoid-associated protein NdpA. | 0.666 |
| SO_2914 | proQ | SO_2914 | SO_2602 | Protein of unknown function DUF412. | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.754 |
| SO_2914 | rraB | SO_2914 | SO_0568 | Protein of unknown function DUF412. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.774 |
| SO_2914 | seqA | SO_2914 | SO_2335 | Protein of unknown function DUF412. | Negative regulator of DNA replication SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.720 |
| SO_2914 | syd | SO_2914 | SO_1609 | Protein of unknown function DUF412. | SecY binding protein Syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.746 |
| SO_2914 | yejL | SO_2914 | SO_2176 | Protein of unknown function DUF412. | Protein of unknown function DUF1414 YejL; Belongs to the UPF0352 family. | 0.766 |
| SO_2914 | yejM | SO_2914 | SO_2175 | Protein of unknown function DUF412. | Putative sulftase with DUF3413 domain YejM. | 0.571 |
| SO_2914 | yihI | SO_2914 | SO_4728 | Protein of unknown function DUF412. | GAP-like protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.780 |
| ndpA | SO_2914 | SO_2177 | SO_2914 | Nucleoid-associated protein NdpA. | Protein of unknown function DUF412. | 0.666 |
| ndpA | proQ | SO_2177 | SO_2602 | Nucleoid-associated protein NdpA. | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.564 |
| ndpA | rlmM | SO_2177 | SO_1536 | Nucleoid-associated protein NdpA. | 23S rRNA (cytidine2498-2'-O)-methyltransferase RlmM; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.720 |
| ndpA | rraB | SO_2177 | SO_0568 | Nucleoid-associated protein NdpA. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.613 |
| ndpA | seqA | SO_2177 | SO_2335 | Nucleoid-associated protein NdpA. | Negative regulator of DNA replication SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated. | 0.688 |
| ndpA | syd | SO_2177 | SO_1609 | Nucleoid-associated protein NdpA. | SecY binding protein Syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.575 |
| ndpA | yejL | SO_2177 | SO_2176 | Nucleoid-associated protein NdpA. | Protein of unknown function DUF1414 YejL; Belongs to the UPF0352 family. | 0.843 |
| ndpA | yejM | SO_2177 | SO_2175 | Nucleoid-associated protein NdpA. | Putative sulftase with DUF3413 domain YejM. | 0.845 |
| ndpA | yggL | SO_2177 | SO_3366 | Nucleoid-associated protein NdpA. | Protein of unknown function DUF469 YggL. | 0.605 |
| ndpA | yihI | SO_2177 | SO_4728 | Nucleoid-associated protein NdpA. | GAP-like protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.730 |
| proQ | SO_2914 | SO_2602 | SO_2914 | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | Protein of unknown function DUF412. | 0.754 |
| proQ | ndpA | SO_2602 | SO_2177 | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | Nucleoid-associated protein NdpA. | 0.564 |