| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0541 | SO_2204 | SO_0541 | SO_2204 | RNA-metabolizing metallo-beta-lactamase family protein. | DNA ligase ATP-dependent. | 0.484 |
| SO_0541 | dnaN | SO_0541 | SO_0009 | RNA-metabolizing metallo-beta-lactamase family protein. | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.445 |
| SO_0541 | polA | SO_0541 | SO_4669 | RNA-metabolizing metallo-beta-lactamase family protein. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.571 |
| SO_2204 | SO_0541 | SO_2204 | SO_0541 | DNA ligase ATP-dependent. | RNA-metabolizing metallo-beta-lactamase family protein. | 0.484 |
| SO_2204 | dnaN | SO_2204 | SO_0009 | DNA ligase ATP-dependent. | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.941 |
| SO_2204 | gmhB | SO_2204 | SO_2851 | DNA ligase ATP-dependent. | DD-heptose 17-bisphosphate phosphatase GmhB. | 0.553 |
| SO_2204 | hisB | SO_2204 | SO_2071 | DNA ligase ATP-dependent. | Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.565 |
| SO_2204 | holB | SO_2204 | SO_2612 | DNA ligase ATP-dependent. | DNA polymerase III delta' subunit HolB. | 0.693 |
| SO_2204 | polA | SO_2204 | SO_4669 | DNA ligase ATP-dependent. | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.924 |
| SO_2204 | polB | SO_2204 | SO_1820 | DNA ligase ATP-dependent. | DNA polymerase II PolB. | 0.756 |
| SO_2204 | sbcC | SO_2204 | SO_2843 | DNA ligase ATP-dependent. | dsDNA exonuclease SbcC. | 0.585 |
| SO_2204 | xni | SO_2204 | SO_1549 | DNA ligase ATP-dependent. | Exodeoxyribonuclease III associated protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.798 |
| SO_2204 | xth | SO_2204 | SO_3037 | DNA ligase ATP-dependent. | Exodeoxyribonuclease III Xth. | 0.702 |
| dnaN | SO_0541 | SO_0009 | SO_0541 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | RNA-metabolizing metallo-beta-lactamase family protein. | 0.445 |
| dnaN | SO_2204 | SO_0009 | SO_2204 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA ligase ATP-dependent. | 0.941 |
| dnaN | holB | SO_0009 | SO_2612 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III delta' subunit HolB. | 0.996 |
| dnaN | polA | SO_0009 | SO_4669 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase I PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.992 |
| dnaN | polB | SO_0009 | SO_1820 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase II PolB. | 0.960 |
| dnaN | xni | SO_0009 | SO_1549 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | Exodeoxyribonuclease III associated protein Xni; Has flap endonuclease activity. During DNA replication, flap endonucleases cleave the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. | 0.879 |
| dnaN | xth | SO_0009 | SO_3037 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | Exodeoxyribonuclease III Xth. | 0.907 |