| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_1136 | rph | SO_1136 | SO_4256 | ATP-dependent RNA helicase DEAD box family; Belongs to the DEAD box helicase family. | Ribonuclease PH Rph; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.409 |
| SO_1136 | yeaB | SO_1136 | SO_2220 | ATP-dependent RNA helicase DEAD box family; Belongs to the DEAD box helicase family. | Nucleoside diphosphate hydrolase YeaB. | 0.423 |
| SO_1136 | yjeF | SO_1136 | SO_0598 | ATP-dependent RNA helicase DEAD box family; Belongs to the DEAD box helicase family. | Hydroxyethylthiazole kinase-related protein YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to [...] | 0.637 |
| SO_1383 | rph | SO_1383 | SO_4256 | ATP-dependent RNA helicase DEAD box family; Belongs to the DEAD box helicase family. | Ribonuclease PH Rph; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.409 |
| SO_1383 | yeaB | SO_1383 | SO_2220 | ATP-dependent RNA helicase DEAD box family; Belongs to the DEAD box helicase family. | Nucleoside diphosphate hydrolase YeaB. | 0.424 |
| SO_1383 | yjeF | SO_1383 | SO_0598 | ATP-dependent RNA helicase DEAD box family; Belongs to the DEAD box helicase family. | Hydroxyethylthiazole kinase-related protein YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to [...] | 0.637 |
| SO_4092 | birA | SO_4092 | SO_0214 | Hydrolase carbon-nitrogen family. | Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.514 |
| SO_4092 | yeaB | SO_4092 | SO_2220 | Hydrolase carbon-nitrogen family. | Nucleoside diphosphate hydrolase YeaB. | 0.431 |
| SO_4092 | yjeF | SO_4092 | SO_0598 | Hydrolase carbon-nitrogen family. | Hydroxyethylthiazole kinase-related protein YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to [...] | 0.430 |
| birA | SO_4092 | SO_0214 | SO_4092 | Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hydrolase carbon-nitrogen family. | 0.514 |
| birA | yeaB | SO_0214 | SO_2220 | Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Nucleoside diphosphate hydrolase YeaB. | 0.609 |
| birA | yjeF | SO_0214 | SO_0598 | Bifunctional biotin operon repressor/biotin-[acetyl-CoA-carboxylase] ligase BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Hydroxyethylthiazole kinase-related protein YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to [...] | 0.457 |
| dbpA | rnr | SO_0897 | SO_3935 | ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | 3'-5' exoribonuclease R Rnr; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.611 |
| dbpA | rph | SO_0897 | SO_4256 | ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Ribonuclease PH Rph; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.405 |
| dbpA | yeaB | SO_0897 | SO_2220 | ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Nucleoside diphosphate hydrolase YeaB. | 0.418 |
| dbpA | yjeF | SO_0897 | SO_0598 | ATP-dependent RNA helicase DbpA; Belongs to the DEAD box helicase family. | Hydroxyethylthiazole kinase-related protein YjeF; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to [...] | 0.640 |
| fumB | pabB | SO_2222 | SO_2221 | Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Para-aminobenzoate synthase aminase component PabB. | 0.679 |
| fumB | yeaB | SO_2222 | SO_2220 | Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Nucleoside diphosphate hydrolase YeaB. | 0.546 |
| pabB | fumB | SO_2221 | SO_2222 | Para-aminobenzoate synthase aminase component PabB. | Anaerobic fumarate hydratase FumB; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.679 |
| pabB | yeaB | SO_2221 | SO_2220 | Para-aminobenzoate synthase aminase component PabB. | Nucleoside diphosphate hydrolase YeaB. | 0.826 |
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