Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ptsIPhosphotransferase system (PTS) phosphoenolpyruvate-protein phosphotransferase PtsI; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (567 aa)    
Predicted Functional Partners:
crr
Phosphotransferase system (PTS) glucose-specific IIA component Crr.
 
 0.999
ptsH
Phosphotransferase system (PTS) phosphocarrier protein HPr PtsH.
 
 0.999
ptsO
Phosphotransferase system (PTS) phosphohisitinoprotein-hexose phosphotransferase comonent PtsO.
 
 
 0.979
ptsG
Phosphotransferase system (PTS) glucose-specific IIBC component PtsG.
  
 0.928
ptsN
Phosphotransferase system (PTS) sugar-specific IIA component PtsN.
 
  
 0.860
cyaA
Adenylate cyclase CyaA; Belongs to the adenylyl cyclase class-1 family.
      
 0.743
pta
Phosphate acetyltransferase Pta; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
   
  
 0.628
eno
Enolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
 
  
 0.625
pgk
Phosphoglycerate kinase Pgk; Belongs to the phosphoglycerate kinase family.
   
  
 0.624
SO_2239
Uncharacterized protein.
       0.594
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.