| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| hisB | hisF | SO_2071 | SO_2068 | Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Imidazole glycerol phosphate synthase cyclase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.999 |
| hisB | suhB | SO_2071 | SO_2260 | Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | Inositol-phosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. | 0.700 |
| hisF | hisB | SO_2068 | SO_2071 | Imidazole glycerol phosphate synthase cyclase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Bifunctional imidazoleglycerol-phosphate dehydratase/histidinol-phosphatase HisB; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. | 0.999 |
| hisF | suhB | SO_2068 | SO_2260 | Imidazole glycerol phosphate synthase cyclase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | Inositol-phosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. | 0.652 |
| nadF | suhB | SO_1523 | SO_2260 | NAD kinase NadF; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | Inositol-phosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. | 0.895 |
| nusA | nusB | SO_1203 | SO_3465 | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.925 |
| nusA | nusG | SO_1203 | SO_0219 | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | 0.990 |
| nusA | rpoB | SO_1203 | SO_0224 | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase beta subunit RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.997 |
| nusA | rpoC | SO_1203 | SO_0225 | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase beta' subunit RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.992 |
| nusA | rpoZ | SO_1203 | SO_0360 | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | DNA-directed RNA polymerase omega subunit RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.952 |
| nusA | rsmB | SO_1203 | SO_0030 | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | 16S rRNA (cytosine967-C5)-methyltransferase RsmB; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.868 |
| nusA | suhB | SO_1203 | SO_2260 | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | Inositol-phosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. | 0.831 |
| nusB | nusA | SO_3465 | SO_1203 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | 0.925 |
| nusB | nusG | SO_3465 | SO_0219 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | 0.957 |
| nusB | rpoB | SO_3465 | SO_0224 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | DNA-directed RNA polymerase beta subunit RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.728 |
| nusB | rpoC | SO_3465 | SO_0225 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | DNA-directed RNA polymerase beta' subunit RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.614 |
| nusB | rpoZ | SO_3465 | SO_0360 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | DNA-directed RNA polymerase omega subunit RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.865 |
| nusB | suhB | SO_3465 | SO_2260 | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Inositol-phosphate phosphatase SuhB; Belongs to the inositol monophosphatase superfamily. | 0.744 |
| nusG | nusA | SO_0219 | SO_1203 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | N utilization substance protein A NusA; Participates in both transcription termination and antitermination. | 0.990 |
| nusG | nusB | SO_0219 | SO_3465 | Transcription antitermination protein NusG; Participates in transcription elongation, termination and antitermination. | Transcription antitermination factor NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 0.957 |