STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fldAFlavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (175 aa)    
Predicted Functional Partners:
ybfE
Ribbon-helix-helix protein repressor CopG family YbfE.
 
  
 0.960
fur
Transcriptional repressor of iron homeostasis Fur; Belongs to the Fur family.
 
  
 0.851
fieF
Cadmium and zinc efflux pump FieF; Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family.
      
 0.783
SO_2332
Protein of unknown function DUF2788.
       0.646
sdhA
Succinate dehydrogenase flavoprotein subunit SdhA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
   
 
 0.621
seqA
Negative regulator of DNA replication SeqA; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
 
  
 0.612
cobO
cob(I)alamin adenosyltransferase CobO; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
     
 0.582
SO_2329
Efp-associated protein of unknown function DUF2331.
  
    0.560
efp
Translation elongation factor P Efp; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.
  
    0.543
prsA
Ribose-phosphate pyrophosphokinase PrsA; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
    0.518
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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