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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadAQuinolinate synthetase NadA; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (357 aa)    
Predicted Functional Partners:
nadC
Nicotinate-nucleotide pyrophosphorylase NadC; Belongs to the NadC/ModD family.
 
 0.999
nadB
L-aspartate oxidase component of quinolinate synthetase NadB; Catalyzes the oxidation of L-aspartate to iminoaspartate.
 0.999
nadD
Nicotinate-nucleotide adenylyltransferase NadD; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
     
 0.889
SO_3058
Flavocytochrome c flavin subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.889
nadE
NH(3)-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.876
pncC
Nicotinamide deamidase PncC; One of the key enzymes of the pyridine nucleotide cycle which permits cells to recycle the by products of NAD consumption back to NAD. Has no activity on NAD, NADP, nicotinamide or nicotinamide riboside.
  
  
 0.867
SO_1674
Short chain dehydrogenase family protein.
  
    0.822
nadV
Nicotinamide phosphoribosyltransferase NadV; Belongs to the NAPRTase family.
  
  
 0.815
pnuT
Thiamin uptake permease PnuT.
  
  
 0.762
cysE
Serine acetyltransferase CysE.
  
    0.694
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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