| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0827 | SO_1522 | SO_0827 | SO_1522 | Lactate transport protein LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | Lactate transport protein LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.478 |
| SO_0827 | yciM | SO_0827 | SO_2399 | Lactate transport protein LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.731 |
| SO_1522 | SO_0827 | SO_1522 | SO_0827 | Lactate transport protein LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | Lactate transport protein LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | 0.478 |
| SO_1522 | yciM | SO_1522 | SO_2399 | Lactate transport protein LctP family; Transports L-lactate across the membrane. Can also transport D-lactate and glycolate; Belongs to the lactate permease family. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.716 |
| ftsB | lpxH | SO_3439 | SO_1789 | Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | UDP-23-diacylglucosamine hydrolase LpxH; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.597 |
| ftsB | yciM | SO_3439 | SO_2399 | Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.658 |
| hemX | slmA | SO_4315 | SO_4251 | uroporphyrin-III C-methyltransferase HemX. | Transcriptional repressor of cell division SlmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | 0.519 |
| hemX | yciM | SO_4315 | SO_2399 | uroporphyrin-III C-methyltransferase HemX. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.597 |
| ihfB | lapA | SO_2401 | SO_2400 | Integration host factor beta subunit IhfB; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Membrane protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.563 |
| ihfB | pyrF | SO_2401 | SO_2398 | Integration host factor beta subunit IhfB; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.798 |
| ihfB | yciM | SO_2401 | SO_2399 | Integration host factor beta subunit IhfB; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.562 |
| lapA | ihfB | SO_2400 | SO_2401 | Membrane protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Integration host factor beta subunit IhfB; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.563 |
| lapA | pyrF | SO_2400 | SO_2398 | Membrane protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.683 |
| lapA | yciM | SO_2400 | SO_2399 | Membrane protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.991 |
| lpxH | ftsB | SO_1789 | SO_3439 | UDP-23-diacylglucosamine hydrolase LpxH; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Cell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.597 |
| lpxH | yciM | SO_1789 | SO_2399 | UDP-23-diacylglucosamine hydrolase LpxH; Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.559 |
| pyrF | ihfB | SO_2398 | SO_2401 | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Integration host factor beta subunit IhfB; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.798 |
| pyrF | lapA | SO_2398 | SO_2400 | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Membrane protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. | 0.683 |
| pyrF | yciM | SO_2398 | SO_2399 | Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. | 0.880 |
| slmA | hemX | SO_4251 | SO_4315 | Transcriptional repressor of cell division SlmA; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. | uroporphyrin-III C-methyltransferase HemX. | 0.519 |
STRING v12.5 is now available!
