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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lapAMembrane protein of unknown function DUF1049; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (91 aa)    
Predicted Functional Partners:
yciM
Predicted N-acetylglucosaminyl transferase YciM; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
  
  
 0.991
bpfA
Biofilm-promoting protein BpfA.
      
 0.919
pyrF
Orotidine 5`-phosphate decarboxylase PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
       0.683
tolC
Global secretion system secretin TolC.
      
 0.651
hlyA
Hemolysin HlyA.
      
 0.610
SO_4323
Bifunctional diguanylate cyclase/phosphodiesterase LasD-like protein.
      
 0.590
SO_4322
T1SS associated periplasmic transglutaminase-like cysteine proteinase.
      
 0.580
SO_4321
Pal-like T1SS-linked outer membrane lipoprotein.
      
 0.577
aggB
Type I protein secretion system MFP component AggB.
      
 0.576
aggA
Type I protein secretion system secretin component AggA.
      
 0.567
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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