| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_2414 | SO_3275 | SO_2414 | SO_3275 | 2-phosphoglycolate phosphatase family. | Putative periplasmic protein. | 0.694 |
| SO_2414 | SO_3635 | SO_2414 | SO_3635 | 2-phosphoglycolate phosphatase family. | Cell wall phosphotransferase. | 0.927 |
| SO_2414 | anmK | SO_2414 | SO_1313 | 2-phosphoglycolate phosphatase family. | anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.922 |
| SO_2414 | crr | SO_2414 | SO_2236 | 2-phosphoglycolate phosphatase family. | Phosphotransferase system (PTS) glucose-specific IIA component Crr. | 0.901 |
| SO_2414 | gyrA | SO_2414 | SO_2411 | 2-phosphoglycolate phosphatase family. | DNA gyrase subunit GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.499 |
| SO_2414 | hisIE | SO_2414 | SO_2067 | 2-phosphoglycolate phosphatase family. | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase HisIE; In the C-terminal section; belongs to the PRA-PH family. | 0.474 |
| SO_2414 | moaA | SO_2414 | SO_4452 | 2-phosphoglycolate phosphatase family. | Molybdenum cofactor biosynthesis protein A MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.521 |
| SO_2414 | moaA-2 | SO_2414 | SO_4724 | 2-phosphoglycolate phosphatase family. | Tungsten cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.521 |
| SO_2414 | serC | SO_2414 | SO_2410 | 2-phosphoglycolate phosphatase family. | Bifunctional 3-phosphoserine aminotransferase/phosphohydroxythreonine SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.496 |
| SO_2414 | ubiG | SO_2414 | SO_2413 | 2-phosphoglycolate phosphatase family. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.832 |
| SO_3275 | SO_2414 | SO_3275 | SO_2414 | Putative periplasmic protein. | 2-phosphoglycolate phosphatase family. | 0.694 |
| SO_3635 | SO_2414 | SO_3635 | SO_2414 | Cell wall phosphotransferase. | 2-phosphoglycolate phosphatase family. | 0.927 |
| anmK | SO_2414 | SO_1313 | SO_2414 | anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 2-phosphoglycolate phosphatase family. | 0.922 |
| anmK | crr | SO_1313 | SO_2236 | anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | Phosphotransferase system (PTS) glucose-specific IIA component Crr. | 0.902 |
| crr | SO_2414 | SO_2236 | SO_2414 | Phosphotransferase system (PTS) glucose-specific IIA component Crr. | 2-phosphoglycolate phosphatase family. | 0.901 |
| crr | anmK | SO_2236 | SO_1313 | Phosphotransferase system (PTS) glucose-specific IIA component Crr. | anhydro-N-acetylmuramic acid kinase AnmK; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.902 |
| gyrA | SO_2414 | SO_2411 | SO_2414 | DNA gyrase subunit GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 2-phosphoglycolate phosphatase family. | 0.499 |
| gyrA | serC | SO_2411 | SO_2410 | DNA gyrase subunit GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Bifunctional 3-phosphoserine aminotransferase/phosphohydroxythreonine SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.817 |
| gyrA | ubiG | SO_2411 | SO_2413 | DNA gyrase subunit GyrA; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | Ubiquinone biosynthesis O-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.705 |
| hisIE | SO_2414 | SO_2067 | SO_2414 | Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase HisIE; In the C-terminal section; belongs to the PRA-PH family. | 2-phosphoglycolate phosphatase family. | 0.474 |