Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sppASignal peptide peptidase SppA. (614 aa)    
Predicted Functional Partners:
ansA
L-asparaginase I AnsA.
      0.801
lepB
Signal peptidase I LepB; Belongs to the peptidase S26 family.
      
 0.687
mlaF
ABC-type phospholipid uptake (salvage) system ATPase component MlaF.
     
 0.672
fadH
NADP-dependent 24-dienoyl-CoA reductase FadH.
       0.628
nupC
Na-dependent nicotinamide ribose transporter NupC.
     
 0.520
bamA
Beta barrel protein translocation component BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
   
  
 0.505
rpsD
30S ribosomal protein S4 RpsD; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
     
 0.487
mrcB
Penicillin-binding protein 1B MrcB; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
      
 0.467
btuB
TonB-dependent vitamin B12 receptor BtuB.
   
  
 0.430
SO_0491
Oligopeptidase lipoprotein M13 family.
   
    0.421
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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