STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sye2NAD(P)H:flavin oxidoreductase Sye2. (362 aa)    
Predicted Functional Partners:
sye1
NADH:flavin oxidoreductase Sye1.
 
 
0.930
ifcA
Periplasmic tetraheme flavocytochrome IfcA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
      0.887
gshB
ATP-dependent glutathione synthetase GshB.
      
 0.871
urdA
FAD-dependent oxidoreductase; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate [...]
 
    0.815
fccA
Periplasmic fumarate reductase FccA; Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO). This enzyme is essentially unidirectional (By similarity); In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
      0.787
sye4
NAD(P)H:flavin oxidoreductase Sye4.
  
  
0.743
sye3
NAD(P)H:flavin oxidoreductase Sye3.
  
 
0.696
nfnB
Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB.
  
 
 0.667
SO_2452
Alcohol dehydrogenase zinc-containing.
  
  
 0.559
yafC
Transcriptional regulator YafC; Belongs to the LysR transcriptional regulatory family.
  
    0.532
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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