Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sye1NADH:flavin oxidoreductase Sye1. (365 aa)    
Predicted Functional Partners:
sye2
NAD(P)H:flavin oxidoreductase Sye2.
 
 
0.930
sye4
NAD(P)H:flavin oxidoreductase Sye4.
  
 
0.742
sye3
NAD(P)H:flavin oxidoreductase Sye3.
  
 
0.727
nfnB
Bifunctional oxygen-insensitive NAD(P)H nitroreductase/dihydropteridine reductase NfnB.
  
 
 0.668
urdA
FAD-dependent oxidoreductase; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate [...]
 
  
 0.588
SO_2452
Alcohol dehydrogenase zinc-containing.
  
  
 0.583
ifcA
Periplasmic tetraheme flavocytochrome IfcA; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
 
  
 0.552
yafC
Transcriptional regulator YafC; Belongs to the LysR transcriptional regulatory family.
  
    0.495
fccA
Periplasmic fumarate reductase FccA; Catalyzes fumarate reduction using artificial electron donors such as methyl viologen. The physiological reductant is unknown, but evidence indicates that flavocytochrome c participates in electron transfer from formate to fumarate and possibly also to trimethylamine oxide (TMAO). This enzyme is essentially unidirectional (By similarity); In the C-terminal section; belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
    
 0.447
etfB
Electron transfer flavoprotein beta subunit EtfB.
  
 
 0.432
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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