STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdnAPolysaccharide biosynthesis protein; Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate); Belongs to the DegT/DnrJ/EryC1 family. (395 aa)    
Predicted Functional Partners:
kdnB
Alcohol dehydrogenase iron-containing; Catalyzes the first step of the biosynthesis of Kdo8N (8- amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate).
  
 0.995
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase KdsB; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family.
 
  
 0.953
kdkA
3-deoxy-D-manno-oct-2-ulosonic acid (KDO) kinase KdkA; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
     
 0.888
aspC-2
Aspartate aminotransferase AspC.
   
  
 0.757
agaO
Sugar oxidoreductase AgaO; Glycosidase that has specific alpha-N-acetylgalactosaminidase activity; Belongs to the Gfo/Idh/MocA family. Glycosyl hydrolase 109 subfamily.
 
  
 0.709
adhB
Alcohol dehydrogenase II AdhB.
 
   
 0.702
pseB
Bifunctional UDP GlcNAc C6 dehydratase/C5 epimerase PseB.
  
 0.692
wbfY
Polysaccharide biosynthesis protein epimerase/dehydratase-like WbfY.
 
  
 0.631
rffG
dTDP-glucose-4,6-dehydratase RffG; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.
 
  
 0.593
SO_2479
Protein of unknown function DUF2897.
  
    0.578
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.