STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
kdnBAlcohol dehydrogenase iron-containing; Catalyzes the first step of the biosynthesis of Kdo8N (8- amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate). (356 aa)    
Predicted Functional Partners:
kdnA
Polysaccharide biosynthesis protein; Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate); Belongs to the DegT/DnrJ/EryC1 family.
  
 0.998
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase KdsB; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family.
 
  
 0.996
kdkA
3-deoxy-D-manno-oct-2-ulosonic acid (KDO) kinase KdkA; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
      
 0.939
frmA
S-(hydroxymethyl)glutathione dehydrogenase FrmA; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
    
 
 0.703
lpxA
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      
 0.605
glgA
Glycogen synthase ADP-glucose transglucosylase GlgA.
   
    0.561
SO_0125
Periplasmic L-asparaginase family protein.
  
     0.536
pepB
Aminopeptidase PepB; Probably plays an important role in intracellular peptide degradation.
   
   0.520
SO_2479
Protein of unknown function DUF2897.
  
    0.518
adhB
Alcohol dehydrogenase II AdhB.
  
   
0.483
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.