STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kdnBAlcohol dehydrogenase iron-containing; Catalyzes the first step of the biosynthesis of Kdo8N (8- amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate). (356 aa)    
Predicted Functional Partners:
kdnA
Polysaccharide biosynthesis protein; Catalyzes the second (last) step of the biosynthesis of Kdo8N (8-amino-3,8-dideoxy-D-manno-octulosonate) from Kdo (3-deoxy-D-manno- octulosonate); Belongs to the DegT/DnrJ/EryC1 family.
  
 0.995
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase KdsB; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family.
 
  
 0.995
kdkA
3-deoxy-D-manno-oct-2-ulosonic acid (KDO) kinase KdkA; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
      
 0.891
frmA
S-(hydroxymethyl)glutathione dehydrogenase FrmA; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily.
   
 
 0.745
glgA
Glycogen synthase ADP-glucose transglucosylase GlgA.
   
    0.592
lpxA
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase LpxA; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      
 0.564
pepB
Aminopeptidase PepB; Probably plays an important role in intracellular peptide degradation.
   
   0.539
SO_0125
Periplasmic L-asparaginase family protein.
  
     0.536
pckA
Phosphoenolpyruvate carboxykinase PckA; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
   
  
 0.522
SO_2479
Protein of unknown function DUF2897.
  
    0.514
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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