STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgl6-phosphogluconolactonase Pgl; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (232 aa)    
Predicted Functional Partners:
edd
6-phosphogluconate dehydratase Edd; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family.
 
 0.999
zwf
Glucose-6-phosphate 1-dehydrogenase Zwf; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
 0.999
eda
Bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase Eda.
  
 0.973
gnd
6-phosphogluconate dehydrogenase decarboxylating Gnd; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
 
 
 0.965
nagA
N-acetylglucosamine-6-phosphate deacetylase NagA; Belongs to the metallo-dependent hydrolases superfamily. NagA family.
  
 
 0.947
pgi
Glucose-6-phosphate isomerase Pgi.
 
 
 0.849
panC
Pantoate--beta-alanine ligase PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
      
 0.782
rbsK
Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
  
 0.778
glpK
Glycerol kinase GlpK; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
  
  
 0.776
glpD
Aerobic glycerol-3-phosphate dehydrogenase GlpD.
   
  
 0.659
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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