| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_2504 | queC | SO_2504 | SO_2503 | Rhombosortase. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.777 |
| SO_2504 | queD | SO_2504 | SO_2179 | Rhombosortase. | Queosine biosynthesis protein QueD. | 0.572 |
| SO_2504 | queE | SO_2504 | SO_2501 | Rhombosortase. | Queuosine biosynthesis radical activating enzyme QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.516 |
| SO_2535 | folE | SO_2535 | SO_4254 | Glutamine amidotransferase class II. | GTP cyclohydrolase I FolE. | 0.918 |
| SO_2535 | queC | SO_2535 | SO_2503 | Glutamine amidotransferase class II. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.922 |
| SO_2535 | queD | SO_2535 | SO_2179 | Glutamine amidotransferase class II. | Queosine biosynthesis protein QueD. | 0.922 |
| flaG | queC | SO_3236 | SO_2503 | Uncharacterized flagella locus protein FlaG. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.491 |
| folE | SO_2535 | SO_4254 | SO_2535 | GTP cyclohydrolase I FolE. | Glutamine amidotransferase class II. | 0.918 |
| folE | nrdG | SO_4254 | SO_2833 | GTP cyclohydrolase I FolE. | Anaerobic ribonucleoside-triphosphate reductase activating protein NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.416 |
| folE | queC | SO_4254 | SO_2503 | GTP cyclohydrolase I FolE. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.950 |
| folE | queD | SO_4254 | SO_2179 | GTP cyclohydrolase I FolE. | Queosine biosynthesis protein QueD. | 0.986 |
| folE | queE | SO_4254 | SO_2501 | GTP cyclohydrolase I FolE. | Queuosine biosynthesis radical activating enzyme QueE; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.547 |
| folE | queF | SO_4254 | SO_1608 | GTP cyclohydrolase I FolE. | NADPH-dependent preQ0 reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.492 |
| nrdG | folE | SO_2833 | SO_4254 | Anaerobic ribonucleoside-triphosphate reductase activating protein NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | GTP cyclohydrolase I FolE. | 0.416 |
| nrdG | queC | SO_2833 | SO_2503 | Anaerobic ribonucleoside-triphosphate reductase activating protein NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.670 |
| nrdG | queD | SO_2833 | SO_2179 | Anaerobic ribonucleoside-triphosphate reductase activating protein NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Queosine biosynthesis protein QueD. | 0.825 |
| nrdG | queF | SO_2833 | SO_1608 | Anaerobic ribonucleoside-triphosphate reductase activating protein NrdG; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | NADPH-dependent preQ0 reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.827 |
| queA | queC | SO_3114 | SO_2503 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.515 |
| queA | queF | SO_3114 | SO_1608 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | NADPH-dependent preQ0 reductase QueF; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.518 |
| queC | SO_2504 | SO_2503 | SO_2504 | Queuosine biosynthesis ATPase QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | Rhombosortase. | 0.777 |