Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SO_2543Two component signal transduction system histidine kinase. (460 aa)    
Predicted Functional Partners:
SO_2540
Two component signal transduction system response regulator.
 
 
 
 0.995
SO_2544
Two component signal transduction system hybrid histidine kinase/response regulator with Hpt domain.
 
 
 0.990
SO_2539
Two component signal transduction system response regulator with cyclic diguanylate phosphodiesterase activity and PAS sensory domain.
  
 
 0.982
SO_2144
NO-binding heme-dependent sensor protein.
 
   
 0.978
SO_2541
Two component signal transduction system response regulator.
 
   0.945
SO_2538
Two component signal transduction system response regulator.
 
    0.848
SO_2542
Signaling protein with FIST domain.
 
    0.827
SO_3306
Two component signal transduction system hybrid histidine kinase.
  
   0.763
cheY
Chemotaxis signal transduction system response regulator CheY.
  
   0.736
cheY-2
Chemotaxis signal transduction system response regulator CheY.
  
 
   0.730
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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