| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0859 | SO_2127 | SO_0859 | SO_2127 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Diguanylate cyclase with response regulator receiver modulation. | 0.992 |
| SO_0859 | SO_2539 | SO_0859 | SO_2539 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator with cyclic diguanylate phosphodiesterase activity and PAS sensory domain. | 0.843 |
| SO_0859 | SO_2540 | SO_0859 | SO_2540 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator. | 0.857 |
| SO_0859 | SO_2543 | SO_0859 | SO_2543 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase. | 0.683 |
| SO_0859 | SO_2544 | SO_0859 | SO_2544 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with Hpt domain. | 0.983 |
| SO_0859 | SO_3759 | SO_0859 | SO_3759 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Diguanylate cyclase with GAF sensory domain. | 0.975 |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.995 |
| SO_0859 | cheY-3 | SO_0859 | SO_2547 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Chemotaxis signal transduction system response regulator CheY. | 0.631 |
| SO_0859 | torS | SO_0859 | SO_1230 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.993 |
| SO_2127 | SO_0859 | SO_2127 | SO_0859 | Diguanylate cyclase with response regulator receiver modulation. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.992 |
| SO_2127 | SO_2539 | SO_2127 | SO_2539 | Diguanylate cyclase with response regulator receiver modulation. | Two component signal transduction system response regulator with cyclic diguanylate phosphodiesterase activity and PAS sensory domain. | 0.724 |
| SO_2127 | SO_2543 | SO_2127 | SO_2543 | Diguanylate cyclase with response regulator receiver modulation. | Two component signal transduction system histidine kinase. | 0.490 |
| SO_2127 | SO_2544 | SO_2127 | SO_2544 | Diguanylate cyclase with response regulator receiver modulation. | Two component signal transduction system hybrid histidine kinase/response regulator with Hpt domain. | 0.962 |
| SO_2127 | SO_3759 | SO_2127 | SO_3759 | Diguanylate cyclase with response regulator receiver modulation. | Diguanylate cyclase with GAF sensory domain. | 0.455 |
| SO_2127 | SO_4002 | SO_2127 | SO_4002 | Diguanylate cyclase with response regulator receiver modulation. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.994 |
| SO_2127 | barA | SO_2127 | SO_3457 | Diguanylate cyclase with response regulator receiver modulation. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.994 |
| SO_2127 | cheY-3 | SO_2127 | SO_2547 | Diguanylate cyclase with response regulator receiver modulation. | Chemotaxis signal transduction system response regulator CheY. | 0.530 |
| SO_2127 | torS | SO_2127 | SO_1230 | Diguanylate cyclase with response regulator receiver modulation. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.992 |
| SO_2539 | SO_0859 | SO_2539 | SO_0859 | Two component signal transduction system response regulator with cyclic diguanylate phosphodiesterase activity and PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.843 |