STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yebGUV induced SOS regulon protein YebG. (99 aa)    
Predicted Functional Partners:
lexA
Bifunctional transcriptional repressor of SOS-response/self-cleaving protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
  
 0.867
ybfE
Ribbon-helix-helix protein repressor CopG family YbfE.
  
   
 0.826
sulA
UV induced cell division inhibitor SulA; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division.
   
  
 0.822
yqcC
tRNA pseudouridine synthase C-associated protein of unknown function DUF446 YqcC.
      
 0.800
rdgC
Putative exonuclease RdgC; May be involved in recombination; Belongs to the RdgC family.
      
 0.798
yebR
Free methionine-R-sulfoxide reductase YebR.
  
    0.797
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.742
SO_0347
Phospholipid/glycerol acyltransferase family protein.
  
     0.713
SO_0348
Phospholipid/glycerol acyltransferase family protein.
  
     0.707
rnhA
Ribonuclease HI RnhA; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
   
  
 0.703
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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