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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ldhLeucine dehydrogenase Ldh. (344 aa)    
Predicted Functional Partners:
gltB
NADPH-dependent glutamate synthase large subunit GltB.
  
 
 0.988
bkdA1
3-methyl-2-oxobutanoate dehydrogenase complex E1 component alpha subunit BkdA1.
  
 
 0.973
bkdA2
3-methyl-2-oxobutanoate dehydrogenase complex E1 component beta subunit BkdA2.
  
 
 0.959
yfbQ
PLP-dependent aminotransferase YfbQ.
  
 
 0.935
ilvE
Branched-chain-amino-acid transaminase IlvE.
  
 
 0.933
leuA
2-isopropylmalate synthase LeuA; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.916
ilvD
Dihydroxy-acid dehydratase IlvD; Belongs to the IlvD/Edd family.
   
 0.915
glsF
Ferredoxin-dependent glutamate synthase GlsF; Belongs to the glutamate synthase family.
  
 
 0.868
cobB
Deacetylase of acetyl-CoA synthetase NAD-dependent CobB; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
    
 0.839
lldR
Transcriptional regulator of L-lactate utilization LldR; Belongs to the LysR transcriptional regulatory family.
    
 
 0.798
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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