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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppsAPhosphoenolpyruvate synthase PpsA; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (789 aa)    
Predicted Functional Partners:
pckA
Phosphoenolpyruvate carboxykinase PckA; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
   
 
 0.970
sfcA
NAD-dependent malate dehydrogenase (oxaloacetate-decarboxylating) SfcA; Belongs to the malic enzymes family.
  
 
 0.968
eno
Enolase Eno; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
  
 
 0.962
ydiA
Putative phosphotransferase YdiA; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
 
  
 0.954
maeB
NADP-dependent malate dehydrogenase (oxaloacetate-decarboxylating) MaeB.
  
 
 0.953
aceE
Pyruvate dehydrogenase E1 component AceE; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 
 0.939
talB
Transaldolase B TalB; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.933
ppc
Phosphoenolpyruvate carboxylase Ppc; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.932
pykA
Pyruvate kinase II PykA; Belongs to the pyruvate kinase family.
     
 0.932
ldhA
Fermentative lactate dehydrogenase NADH dependent LdhA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
    
 0.916
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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