| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0352 | SO_0859 | SO_0352 | SO_0859 | Two component signal transduction system histidine kinase. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.476 |
| SO_0352 | SO_2648 | SO_0352 | SO_2648 | Two component signal transduction system histidine kinase. | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | 0.789 |
| SO_0352 | SO_4002 | SO_0352 | SO_4002 | Two component signal transduction system histidine kinase. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.552 |
| SO_0859 | SO_0352 | SO_0859 | SO_0352 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system histidine kinase. | 0.476 |
| SO_0859 | SO_2648 | SO_0859 | SO_2648 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | 0.806 |
| SO_0859 | SO_4002 | SO_0859 | SO_4002 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.995 |
| SO_0859 | SO_4445 | SO_0859 | SO_4445 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Two component signal transduction system hybrid histidine kinase/response regulator. | 0.990 |
| SO_0859 | barA | SO_0859 | SO_3457 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.995 |
| SO_0859 | prlS | SO_0859 | SO_2742 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS. | 0.989 |
| SO_0859 | torS | SO_0859 | SO_1230 | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.993 |
| SO_2648 | SO_0352 | SO_2648 | SO_0352 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Two component signal transduction system histidine kinase. | 0.789 |
| SO_2648 | SO_0859 | SO_2648 | SO_0859 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.806 |
| SO_2648 | SO_4002 | SO_2648 | SO_4002 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Two component signal transduction system hybrid histidine kinase/response regulator with PAS sensory domain. | 0.887 |
| SO_2648 | SO_4445 | SO_2648 | SO_4445 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Two component signal transduction system hybrid histidine kinase/response regulator. | 0.634 |
| SO_2648 | acs | SO_2648 | SO_2743 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Acetyl-coenzyme A synthetase AcsA; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.678 |
| SO_2648 | argE | SO_2648 | SO_3749 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | N-acetyl-L-ornithine deacetylase ArgE. | 0.824 |
| SO_2648 | barA | SO_2648 | SO_3457 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Histidine kinase; Two component signal transduction system hybrid histidine kinase/response regulator with DUF2222 and Hpt domains BarA. | 0.855 |
| SO_2648 | fadI | SO_2648 | SO_3089 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Anaerobic fatty oxidation complex beta subunit FadI; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. | 0.785 |
| SO_2648 | prlS | SO_2648 | SO_2742 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Proline-responsive two component signal transduction system hybrid histidine kinase/resposne regulator PrlS. | 0.994 |
| SO_2648 | torS | SO_2648 | SO_1230 | Two component signal transduction system response regulator activating acetyl-CoA synthase LuxR family. | Histidine kinase; TMAO-responsive two component signal transduction system hybrid histidine kinase/response regulator TorS. | 0.750 |