| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| mlaC | rraB | SO_3951 | SO_0568 | ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.607 |
| mlaC | tolA | SO_3951 | SO_2749 | ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC. | TolA energy-transducing system inner membrane component TolA. | 0.589 |
| mlaC | tolB | SO_3951 | SO_2748 | ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC. | TonB biopolymer transport system periplasmic component TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.679 |
| mlaC | ybgF | SO_3951 | SO_2746 | ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC. | TolA energy-transducing system periplasmic component YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.570 |
| nagZ | tolA | SO_2250 | SO_2749 | beta-N-acetylglucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | TolA energy-transducing system inner membrane component TolA. | 0.674 |
| pal | tolA | SO_2747 | SO_2749 | Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | TolA energy-transducing system inner membrane component TolA. | 0.672 |
| pal | tolB | SO_2747 | SO_2748 | Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | TonB biopolymer transport system periplasmic component TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.997 |
| pal | tolQ | SO_2747 | SO_2751 | Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | TolA energy-transducing system inner membrane component TolQ; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.981 |
| pal | tolR | SO_2747 | SO_2750 | Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | TolA energy-transducing system inner membrane component TolR; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.971 |
| pal | ybgC | SO_2747 | SO_2752 | Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | TolA energy-transducing system-associated acyl-CoA thioesterase YbgC. | 0.666 |
| pal | ybgF | SO_2747 | SO_2746 | Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | TolA energy-transducing system periplasmic component YbgF; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. | 0.970 |
| rbfA | tolA | SO_1205 | SO_2749 | Ribosome-binding factor A RbfA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | TolA energy-transducing system inner membrane component TolA. | 0.594 |
| rraB | mlaC | SO_0568 | SO_3951 | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC. | 0.607 |
| rraB | tolA | SO_0568 | SO_2749 | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | TolA energy-transducing system inner membrane component TolA. | 0.574 |
| tolA | mlaC | SO_2749 | SO_3951 | TolA energy-transducing system inner membrane component TolA. | ABC-type phospholipid uptake (salvage) system periplasmic chaperone MlaC. | 0.589 |
| tolA | nagZ | SO_2749 | SO_2250 | TolA energy-transducing system inner membrane component TolA. | beta-N-acetylglucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.674 |
| tolA | pal | SO_2749 | SO_2747 | TolA energy-transducing system inner membrane component TolA. | Peptidoglycan-associated lipoprotein Pal; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.672 |
| tolA | rbfA | SO_2749 | SO_1205 | TolA energy-transducing system inner membrane component TolA. | Ribosome-binding factor A RbfA; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.594 |
| tolA | rraB | SO_2749 | SO_0568 | TolA energy-transducing system inner membrane component TolA. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.574 |
| tolA | tolB | SO_2749 | SO_2748 | TolA energy-transducing system inner membrane component TolA. | TonB biopolymer transport system periplasmic component TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. | 0.883 |