| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0776 | hflD | SO_0776 | SO_2634 | YecA family protein; Belongs to the UPF0149 family. | High frequency lysogenization protein HflD. | 0.531 |
| SO_0776 | rnt | SO_0776 | SO_2755 | YecA family protein; Belongs to the UPF0149 family. | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.692 |
| SO_0776 | zipA | SO_0776 | SO_2897 | YecA family protein; Belongs to the UPF0149 family. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.659 |
| dnaE | dnaN | SO_1644 | SO_0009 | DNA polymerase III alpha subunit DnaE. | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.997 |
| dnaE | dnaX | SO_1644 | SO_2013 | DNA polymerase III alpha subunit DnaE. | DNA polymerase III gamma and tau subunits DnaX. | 0.998 |
| dnaE | rnt | SO_1644 | SO_2755 | DNA polymerase III alpha subunit DnaE. | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.737 |
| dnaN | dnaE | SO_0009 | SO_1644 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III alpha subunit DnaE. | 0.997 |
| dnaN | dnaX | SO_0009 | SO_2013 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | DNA polymerase III gamma and tau subunits DnaX. | 0.997 |
| dnaN | rnt | SO_0009 | SO_2755 | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.711 |
| dnaX | dnaE | SO_2013 | SO_1644 | DNA polymerase III gamma and tau subunits DnaX. | DNA polymerase III alpha subunit DnaE. | 0.998 |
| dnaX | dnaN | SO_2013 | SO_0009 | DNA polymerase III gamma and tau subunits DnaX. | DNA polymerase III beta subunit DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiatio [...] | 0.997 |
| dnaX | rnt | SO_2013 | SO_2755 | DNA polymerase III gamma and tau subunits DnaX. | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.672 |
| hflD | SO_0776 | SO_2634 | SO_0776 | High frequency lysogenization protein HflD. | YecA family protein; Belongs to the UPF0149 family. | 0.531 |
| hflD | rnt | SO_2634 | SO_2755 | High frequency lysogenization protein HflD. | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.709 |
| hflD | zipA | SO_2634 | SO_2897 | High frequency lysogenization protein HflD. | Cell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. | 0.540 |
| kdsA | nadE | SO_3827 | SO_2021 | 2-dehydro-3-deoxyphosphooctonate aldolase KdsA; Belongs to the KdsA family. | NH(3)-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.863 |
| kdsA | rnt | SO_3827 | SO_2755 | 2-dehydro-3-deoxyphosphooctonate aldolase KdsA; Belongs to the KdsA family. | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.739 |
| nadE | kdsA | SO_2021 | SO_3827 | NH(3)-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 2-dehydro-3-deoxyphosphooctonate aldolase KdsA; Belongs to the KdsA family. | 0.863 |
| nadE | rnt | SO_2021 | SO_2755 | NH(3)-dependent NAD(+) synthetase NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.697 |
| rnd | rnt | SO_2580 | SO_2755 | Ribonuclease D Rnd; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | Ribonuclease T Rnt; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. | 0.684 |