Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tsaAPeroxiredoxin TsaA. (201 aa)    
Predicted Functional Partners:
ahpF
Alkyl hydroperoxide reductase flavoprotein component AhpF.
  
  
 0.868
SO_4640
Antioxidant AhpC/Tsa family; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
   
 0.850
trxB
Thioredoxin reductase TrxB.
  
 
 0.833
sodB
Fe/Mn superoxide dismutase SodB; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
  
 0.711
fur
Transcriptional repressor of iron homeostasis Fur; Belongs to the Fur family.
  
  
 0.648
katB
Catalase HPII KatB; Belongs to the catalase family.
  
 
 0.639
clpA
ATP-dependent Clp protease ATPase and specificity subunit ClpA; Belongs to the ClpA/ClpB family.
  
 
 0.597
dpsA
DNA-binding ferritin-like protein (oxidative damage protectant) DpsA; Belongs to the Dps family.
  
  
 0.588
ftn
Ferritin Ftn; Iron-storage protein.
  
  
 0.576
azrR
Superoxide-responsive transcriptional repressor of superoxide stress response AzrR.
  
    0.574
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.