STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypRTranscriptional regulator of proline and 4-hydroxyproline utilization HypR. (223 aa)    
Predicted Functional Partners:
pdhR
Transcriptional repressor of pyruvate metabolism PdhR.
 
  
 0.821
hmgR
Homogentisate-responsive transcriptional repressor of homogenetisate degradation HmgR; Belongs to the LysR transcriptional regulatory family.
   
  
 0.711
hutC
Transcriptional repressor of histidine utilization genes HutC.
  
   
 0.668
ilvH
Acetolactate synthase III small subunit IlvH.
  
    0.578
fabH-2
3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family.
       0.535
hypE
NiFe hydrogenase accessory/formation protein HypE.
      
 0.510
hypD
NiFe hydrogenase expression/formation protein HypD; Belongs to the HypD family.
      
 0.510
ampP
Aminopeptidase P AmpP.
     
 0.499
fadR
Transcriptional regulator of fatty acid metabolism FadR; Multifunctional regulator of fatty acid metabolism.
  
  
 0.484
trpR
Transcriptional repressor of aromatic amino acid biosynthesis TrpR.
   
  
 0.480
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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