Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yfgCPeriplasmic Zn-dependent protease YfgC; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (489 aa)    
Predicted Functional Partners:
arsC
Glutaredoxin-dependent arsenate reductase ArsC.
 
  
 0.863
SO_2872
Membrane protein of unknown function DUF2069.
 
   
 0.632
dsbA
Periplasmic thiol:disulfide interchange protein DsbA.
 
  
 0.610
SO_0048
Predicted non-catalytic member of peptidase subfamily M23B.
 
 
   0.596
surA
Outer membrane protein maturation factor peptidyl-prolyl cis-trans isomerase SurA; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
  
 0.583
SO_2868
SirA-like protein; Belongs to the sulfur carrier protein TusA family.
       0.576
lptD
Lipopolysaccharide export porin LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
  
  
 0.563
yfgO
Predicted inner membrane permease UPF0118 family YfgO.
       0.508
SO_3560
Predicted non-catalytic member of peptidase subfamily M16B.
  
    0.502
SO_3718
Thiol:disulfide interchange protein DsbA family.
 
    0.470
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: medium (66%) [HD]