Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
focABidirectional formate transporter FocA. (324 aa)    
Predicted Functional Partners:
can
Beta-class carbonic anhydrase Can; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
  
    0.821
pflB
Pyruvate formate-lyase PflB.
 
  
 0.770
dld
Respiratory FAD-dependent D-lactate dehydrogenase Dld.
     
 0.734
pflA
Pyruvate formate-lyase 1 activating enzyme PflA; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 0.712
fadH
NADP-dependent 24-dienoyl-CoA reductase FadH.
     
 0.670
lpdA
Dihydrolipoamide dehydrogenase LpdA.
  
 
 0.664
pdhR
Transcriptional repressor of pyruvate metabolism PdhR.
      
 0.663
napA
Periplasmic nitrate reductase molybdopterin-binding subunit NapA; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite.
 
  
 0.621
cydA
Cytochrome d ubiquinol oxidase subunit I CydA.
   
  
 0.605
glnK
Regulatory protein for nitrogen assimilation GlnK; Belongs to the P(II) protein family.
   
  
 0.491
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (16%) [HD]