node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SO_2872 | SO_2914 | SO_2872 | SO_2914 | Membrane protein of unknown function DUF2069. | Protein of unknown function DUF412. | 0.744 |
SO_2872 | hptA | SO_2872 | SO_1327 | Membrane protein of unknown function DUF2069. | Histidine-containing phosphotransfer domain protein HptA. | 0.579 |
SO_2872 | metJ | SO_2872 | SO_4057 | Membrane protein of unknown function DUF2069. | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.446 |
SO_2872 | nlpI | SO_2872 | SO_1210 | Membrane protein of unknown function DUF2069. | Globular tetratricopeptide repeat containing lipoprotein NlpI; May be involved in cell division. | 0.557 |
SO_2872 | proQ | SO_2872 | SO_2602 | Membrane protein of unknown function DUF2069. | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.601 |
SO_2872 | rraB | SO_2872 | SO_0568 | Membrane protein of unknown function DUF2069. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.675 |
SO_2872 | rseA | SO_2872 | SO_1343 | Membrane protein of unknown function DUF2069. | sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...] | 0.533 |
SO_2872 | syd | SO_2872 | SO_1609 | Membrane protein of unknown function DUF2069. | SecY binding protein Syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.575 |
SO_2872 | yejL | SO_2872 | SO_2176 | Membrane protein of unknown function DUF2069. | Protein of unknown function DUF1414 YejL; Belongs to the UPF0352 family. | 0.623 |
SO_2872 | yihI | SO_2872 | SO_4728 | Membrane protein of unknown function DUF2069. | GAP-like protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.628 |
SO_2914 | SO_2872 | SO_2914 | SO_2872 | Protein of unknown function DUF412. | Membrane protein of unknown function DUF2069. | 0.744 |
SO_2914 | hptA | SO_2914 | SO_1327 | Protein of unknown function DUF412. | Histidine-containing phosphotransfer domain protein HptA. | 0.771 |
SO_2914 | metJ | SO_2914 | SO_4057 | Protein of unknown function DUF412. | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.762 |
SO_2914 | nlpI | SO_2914 | SO_1210 | Protein of unknown function DUF412. | Globular tetratricopeptide repeat containing lipoprotein NlpI; May be involved in cell division. | 0.761 |
SO_2914 | proQ | SO_2914 | SO_2602 | Protein of unknown function DUF412. | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.754 |
SO_2914 | rraB | SO_2914 | SO_0568 | Protein of unknown function DUF412. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.774 |
SO_2914 | rseA | SO_2914 | SO_1343 | Protein of unknown function DUF412. | sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...] | 0.765 |
SO_2914 | syd | SO_2914 | SO_1609 | Protein of unknown function DUF412. | SecY binding protein Syd; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family. | 0.746 |
SO_2914 | yejL | SO_2914 | SO_2176 | Protein of unknown function DUF412. | Protein of unknown function DUF1414 YejL; Belongs to the UPF0352 family. | 0.766 |
SO_2914 | yihI | SO_2914 | SO_4728 | Protein of unknown function DUF412. | GAP-like protein YihI; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.780 |