| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_0776 | rumA | SO_0776 | SO_3456 | YecA family protein; Belongs to the UPF0149 family. | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | 0.437 |
| SO_0776 | sdhE | SO_0776 | SO_1339 | YecA family protein; Belongs to the UPF0149 family. | Protein of unknown function DUF339; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well. | 0.619 |
| SO_0776 | sohB | SO_0776 | SO_2933 | YecA family protein; Belongs to the UPF0149 family. | Inner membrane anchored endopeptidase SohB. | 0.465 |
| SO_2932 | SO_2934 | SO_2932 | SO_2934 | Transcriptional regulator AraC family. | Extracellular lipase Pla-1/cef family. | 0.414 |
| SO_2932 | sohB | SO_2932 | SO_2933 | Transcriptional regulator AraC family. | Inner membrane anchored endopeptidase SohB. | 0.448 |
| SO_2934 | SO_2932 | SO_2934 | SO_2932 | Extracellular lipase Pla-1/cef family. | Transcriptional regulator AraC family. | 0.414 |
| SO_2934 | sohB | SO_2934 | SO_2933 | Extracellular lipase Pla-1/cef family. | Inner membrane anchored endopeptidase SohB. | 0.604 |
| rbsK | sohB | SO_0810 | SO_2933 | Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | Inner membrane anchored endopeptidase SohB. | 0.501 |
| rbsK | tusE | SO_0810 | SO_2379 | Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | tRNA 2-thiouridine synthesizing protein sulfur mediator TusE; Part of a sulfur-relay system. | 0.479 |
| rbsK | yidD | SO_0810 | SO_0005 | Ribokinase RbsK; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | Membrane insertion associated protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.491 |
| rumA | SO_0776 | SO_3456 | SO_0776 | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | YecA family protein; Belongs to the UPF0149 family. | 0.437 |
| rumA | sohB | SO_3456 | SO_2933 | 23S rRNA (uracil1939-C5)-methyltransferase RumA; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. | Inner membrane anchored endopeptidase SohB. | 0.699 |
| sdhE | SO_0776 | SO_1339 | SO_0776 | Protein of unknown function DUF339; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well. | YecA family protein; Belongs to the UPF0149 family. | 0.619 |
| sdhE | sohB | SO_1339 | SO_2933 | Protein of unknown function DUF339; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well. | Inner membrane anchored endopeptidase SohB. | 0.452 |
| secG | sohB | SO_1201 | SO_2933 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Inner membrane anchored endopeptidase SohB. | 0.882 |
| secG | tusE | SO_1201 | SO_2379 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | tRNA 2-thiouridine synthesizing protein sulfur mediator TusE; Part of a sulfur-relay system. | 0.469 |
| secG | yccA | SO_1201 | SO_2375 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Integral membrane FtsH interacting protein YccA; Belongs to the BI1 family. | 0.699 |
| secG | yidD | SO_1201 | SO_0005 | Preprotein translocase subunit SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Membrane insertion associated protein YidD; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. | 0.914 |
| sohB | SO_0776 | SO_2933 | SO_0776 | Inner membrane anchored endopeptidase SohB. | YecA family protein; Belongs to the UPF0149 family. | 0.465 |
| sohB | SO_2932 | SO_2933 | SO_2932 | Inner membrane anchored endopeptidase SohB. | Transcriptional regulator AraC family. | 0.448 |