Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
croLambda phage transcriptional repressor of early genes Cro. (75 aa)    
Predicted Functional Partners:
cII
Lambda phage phage regulatory protein CII.
  
    0.721
SO_2986
Lambda phage uncharacterized protein.
  
    0.714
SO_2987
Lambda phage uncharacterized protein.
  
    0.712
SO_0063
Toxin-antitoxin system toxin HipA family.
   
   0.684
hipA
Toxin-antitoxin system toxin HipA family; Toxic component of a type II toxin-antitoxin (TA) system; overexpression in wild-type temporarily inhibits cell growth, overexpression in a hipAB deletion leads to acute growth inhibition. The toxic effect of HipA is neutralized by its cognate antitoxin HipB. In the ternary phosphoserine-HipA-HipB-DNA complex the DNA is bent about 125 degrees; all HipA in the crystallized ternary complex is phosphorylated. In E.coli phosphorylation of HipA is thought to release HipB from the HipA-HipB-DNA complex, suggesting the complex functions differently in [...]
   
   0.684
SO_3170
Toxin-antitoxin system toxin HipA family.
   
   0.684
cI
Lambda phage lytic gene repressor CI.
     
 0.608
SO_2978
Lambda phage integrase; Belongs to the 'phage' integrase family.
  
    0.575
SO_2982
Lambda phage uncharacterized protein.
  
    0.569
SO_2981
Lambda phage uncharacterized protein.
  
    0.562
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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