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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SO_3057Phenylalanine/histidine ammonia-lyase family protein. (545 aa)    
Predicted Functional Partners:
hutU
Urocanate hydratase HutU; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
 0.992
hutH
Histidine ammonia-lyase HutH; Belongs to the PAL/histidase family.
  
 
0.944
SO_4374
Phenylalanine/tyrosine ammonia-lyase.
  
  
 
0.929
artQ
ABC-type arginine uptakesystem permease component ArtQ.
   
  
 0.920
artI
ABC-type arginine uptakesystem substrate-binding component ArtI; Belongs to the bacterial solute-binding protein 3 family.
   
  
 0.918
hisD
Histidinol dehydrogenase HisD; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
    
 0.913
hutI
Imidazolonepropionase HutI; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.905
urdA
FAD-dependent oxidoreductase; Catalyzes the two-electron reduction of urocanate to dihydrourocanate (also named imidazole propionate or deamino- histidine). The physiological electron donor is unknown; it might be the membrane-bound tetraheme cytochrome c (CymA). Enables anaerobic growth with urocanate as a sole terminal electron acceptor, and thus can provide the cells with a niche where no other bacteria can compete and survive. Is unable to reduce cinnamate and other unsaturated organic acids such as acrylic, crotonic, fumaric and orotic acids. Has no fumarate reductase or succinate [...]
   
 
  0.905
SO_3058
Flavocytochrome c flavin subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
    0.672
SO_3056
Flavocytochrome c heme submit.
  
    0.670
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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