| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fimV | folC | SO_3069 | SO_3067 | Type IV pilus assembly protein FimV. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | 0.558 |
| fimV | truA | SO_3069 | SO_3068 | Type IV pilus assembly protein FimV. | tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.848 |
| folC | fimV | SO_3067 | SO_3069 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | Type IV pilus assembly protein FimV. | 0.558 |
| folC | rpoA | SO_3067 | SO_0256 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.424 |
| folC | thiDE | SO_3067 | SO_2444 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | Bifunctional hydroxy-(phospho)methylpyrimidine kinase/thiamine-phosphate pyrophosphorylase ThiDE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.416 |
| folC | trpA | SO_3067 | SO_3024 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.774 |
| folC | trpCF | SO_3067 | SO_3022 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | Bifunctional indole-3-glycerolphosphate synthetase/phosphoribosylanthranilate isomerase TrpCF; Belongs to the TrpC family. | 0.886 |
| folC | trpD | SO_3067 | SO_3021 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | Anthranilate phosphoribosyltransferase TrpD; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.611 |
| folC | truA | SO_3067 | SO_3068 | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.942 |
| rplQ | rpoA | SO_0257 | SO_0256 | 50S ribosomal protein L17 RplQ. | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rplQ | truA | SO_0257 | SO_3068 | 50S ribosomal protein L17 RplQ. | tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.879 |
| rplQ | truB | SO_0257 | SO_1206 | 50S ribosomal protein L17 RplQ. | tRNA pseudouridine55 synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.697 |
| rpoA | folC | SO_0256 | SO_3067 | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | 0.424 |
| rpoA | rplQ | SO_0256 | SO_0257 | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 50S ribosomal protein L17 RplQ. | 0.999 |
| rpoA | truA | SO_0256 | SO_3068 | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.868 |
| rpoA | truB | SO_0256 | SO_1206 | DNA-directed RNA polymerase alpha subunit RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | tRNA pseudouridine55 synthase TruB; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.754 |
| rsmH | truA | SO_4227 | SO_3068 | 16S rRNA (cytosine1402-N4)-methyltransferase RsmH; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.797 |
| thiDE | folC | SO_2444 | SO_3067 | Bifunctional hydroxy-(phospho)methylpyrimidine kinase/thiamine-phosphate pyrophosphorylase ThiDE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | 0.416 |
| thiDE | truA | SO_2444 | SO_3068 | Bifunctional hydroxy-(phospho)methylpyrimidine kinase/thiamine-phosphate pyrophosphorylase ThiDE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | tRNA pseudouridine38-40 synthase TruA; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. | 0.702 |
| trpA | folC | SO_3024 | SO_3067 | Tryptophan synthase alpha subunit TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | Bifunctional folylpolyglutamate synthase/dihydrofolate synthase FolC; Belongs to the folylpolyglutamate synthase family. | 0.774 |