Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
asdAspartate semialdehyde dehydrogenese Asd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (338 aa)    
Predicted Functional Partners:
thrA
Bifunctional aspartokinase I / homoserine dehydrogenase I ThrA; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.998
metL
Bifunctional aspartokinase II/homoserine dehydrogenase methionine-sensitive MetL; In the C-terminal section; belongs to the homoserine dehydrogenase family.
 
 0.998
lysC
Lysine-sensitive aspartokinase III LysC; Belongs to the aspartokinase family.
 
 
 0.995
dapA
Dihydrodipicolinate synthase DapA; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
 
 
 0.994
SO_3427
Lysine-sensitive monofunctional aspartokinase LysC family; Belongs to the aspartokinase family.
 
 
 0.992
thrC
Threonine synthase ThrC.
  
 
 0.935
dapB
Dihydrodipicolinate reductase DapB; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
 
  
 0.898
thrB
Homoserine kinase ThrB; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
  
 0.894
pdxB
Erythronate-4-phosphate dehydrogenase PdxB; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate.
  
 
 0.861
argG
Argininosuccinate synthase ArgG; Belongs to the argininosuccinate synthase family. Type 1 subfamily.
  
  
 0.853
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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