| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| metJ | proQ | SO_4057 | SO_2602 | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | 0.743 |
| metJ | rraB | SO_4057 | SO_0568 | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.778 |
| metJ | yfcN | SO_4057 | SO_3081 | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | UPF0115 family protein YfcN; Belongs to the UPF0115 family. | 0.587 |
| prmB | rplD | SO_3080 | SO_0232 | 50S subunit L3 protein glutamine methyltransferase PrmB; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.405 |
| prmB | yfcN | SO_3080 | SO_3081 | 50S subunit L3 protein glutamine methyltransferase PrmB; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | UPF0115 family protein YfcN; Belongs to the UPF0115 family. | 0.626 |
| proQ | metJ | SO_2602 | SO_4057 | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | Transcriptional repressor of methionine metabolism MetJ; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family. | 0.743 |
| proQ | rraB | SO_2602 | SO_0568 | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | Ribonuclease E inhibitor RraB; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome. | 0.782 |
| proQ | yfcN | SO_2602 | SO_3081 | Activator protein ProQ; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities; Belongs to the ProQ family. | UPF0115 family protein YfcN; Belongs to the UPF0115 family. | 0.485 |
| rplD | prmB | SO_0232 | SO_3080 | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 50S subunit L3 protein glutamine methyltransferase PrmB; Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue; Belongs to the protein N5-glutamine methyltransferase family. PrmB subfamily. | 0.405 |
| rplD | rplQ | SO_0232 | SO_0257 | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 50S ribosomal protein L17 RplQ. | 0.998 |
| rplD | rpsG | SO_0232 | SO_0227 | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 30S ribosomal protein S7 RpsG; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.998 |
| rplD | rpsJ | SO_0232 | SO_0230 | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 30S ribosomal protein S10 RpsJ; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.999 |
| rplD | rpsL | SO_0232 | SO_0226 | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 30S ribosomal protein S12p RpsL; With S4 and S5 plays an important role in translational accuracy. | 0.999 |
| rplD | rpsU | SO_0232 | SO_1288 | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 30S ribosomal protein S21 RpsU; Belongs to the bacterial ribosomal protein bS21 family. | 0.956 |
| rplD | yfcN | SO_0232 | SO_3081 | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | UPF0115 family protein YfcN; Belongs to the UPF0115 family. | 0.541 |
| rplQ | rplD | SO_0257 | SO_0232 | 50S ribosomal protein L17 RplQ. | 50S ribosomal protein L4 RplD; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. | 0.998 |
| rplQ | rpsG | SO_0257 | SO_0227 | 50S ribosomal protein L17 RplQ. | 30S ribosomal protein S7 RpsG; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.997 |
| rplQ | rpsJ | SO_0257 | SO_0230 | 50S ribosomal protein L17 RplQ. | 30S ribosomal protein S10 RpsJ; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. | 0.997 |
| rplQ | rpsL | SO_0257 | SO_0226 | 50S ribosomal protein L17 RplQ. | 30S ribosomal protein S12p RpsL; With S4 and S5 plays an important role in translational accuracy. | 0.997 |
| rplQ | rpsU | SO_0257 | SO_1288 | 50S ribosomal protein L17 RplQ. | 30S ribosomal protein S21 RpsU; Belongs to the bacterial ribosomal protein bS21 family. | 0.972 |
STRING v12.5 is now available!
