STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SO_3096RNA polymerase sigma factor ECF family 28; Belongs to the sigma-70 factor family. ECF subfamily. (187 aa)    
Predicted Functional Partners:
SO_3551
RNA polymerase sigma-70 factor ECF subfamily.
  
   
 0.924
SO_1986
RNA polymerase sigma factor ECF family 11; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.920
SO_3097
Anti-sigma factor.
 
    0.915
rseA
sigma-E factor negative regulatory protein RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplas [...]
 
 
 0.897
SO_2009
Protein of unknown function DUF2063.
 
    0.837
chrR
anti-ECFsigma factor ChrR.
 
 
 0.811
rseB
Sigma E factor regulatory protein RseB.
  
 
 0.801
rpoE
RNA polymerase sigma factor 24 RpoE; Belongs to the sigma-70 factor family. ECF subfamily.
  
   
 0.784
rseC
Sigma E factor positive regulatory protein RseC.
     
 0.736
rpoC
DNA-directed RNA polymerase beta' subunit RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.646
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.