| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SO_2290 | SO_3118 | SO_2290 | SO_3118 | Rhodanese domain protein UPF0176 family; Belongs to the UPF0176 family. | 23S rRNA pseudouridine synthase RluA family. | 0.791 |
| SO_3117 | SO_3118 | SO_3117 | SO_3118 | Thioredoxin. | 23S rRNA pseudouridine synthase RluA family. | 0.565 |
| SO_3118 | SO_2290 | SO_3118 | SO_2290 | 23S rRNA pseudouridine synthase RluA family. | Rhodanese domain protein UPF0176 family; Belongs to the UPF0176 family. | 0.791 |
| SO_3118 | SO_3117 | SO_3118 | SO_3117 | 23S rRNA pseudouridine synthase RluA family. | Thioredoxin. | 0.565 |
| SO_3118 | obgE | SO_3118 | SO_3649 | 23S rRNA pseudouridine synthase RluA family. | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.529 |
| SO_3118 | prfA | SO_3118 | SO_3833 | 23S rRNA pseudouridine synthase RluA family. | Peptide chain release factor 1 PrfA; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.558 |
| SO_3118 | prfB | SO_3118 | SO_0991 | 23S rRNA pseudouridine synthase RluA family. | Peptide chain release factor 2 PrfB; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.423 |
| SO_3118 | rlmB | SO_3118 | SO_3934 | 23S rRNA pseudouridine synthase RluA family. | 23S rRNA (guanosine2251-2'-O)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.480 |
| SO_3118 | rplC | SO_3118 | SO_0231 | 23S rRNA pseudouridine synthase RluA family. | 50S ribosomal protein L3 RplC; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.483 |
| SO_3118 | rplT | SO_3118 | SO_2302 | 23S rRNA pseudouridine synthase RluA family. | 50S ribosomal protein L20 RplT; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.557 |
| SO_3118 | rplU | SO_3118 | SO_3652 | 23S rRNA pseudouridine synthase RluA family. | 50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.510 |
| SO_3118 | rsmH | SO_3118 | SO_4227 | 23S rRNA pseudouridine synthase RluA family. | 16S rRNA (cytosine1402-N4)-methyltransferase RsmH; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.433 |
| obgE | SO_3118 | SO_3649 | SO_3118 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 23S rRNA pseudouridine synthase RluA family. | 0.529 |
| obgE | prfA | SO_3649 | SO_3833 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Peptide chain release factor 1 PrfA; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.753 |
| obgE | prfB | SO_3649 | SO_0991 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Peptide chain release factor 2 PrfB; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. | 0.579 |
| obgE | rlmB | SO_3649 | SO_3934 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 23S rRNA (guanosine2251-2'-O)-methyltransferase RlmB; Specifically methylates the ribose of guanosine 2251 in 23S rRNA. | 0.475 |
| obgE | rplC | SO_3649 | SO_0231 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L3 RplC; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.871 |
| obgE | rplT | SO_3649 | SO_2302 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L20 RplT; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. | 0.964 |
| obgE | rplU | SO_3649 | SO_3652 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 50S ribosomal protein L21 RplU; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.978 |
| obgE | rsmH | SO_3649 | SO_4227 | 50S ribosome assembly GTPase ObgE; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 16S rRNA (cytosine1402-N4)-methyltransferase RsmH; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. | 0.522 |
