STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hutDPutative histidine degradation protein HutD. (255 aa)    
Predicted Functional Partners:
hutC
Transcriptional repressor of histidine utilization genes HutC.
 
  
 0.941
hutU
Urocanate hydratase HutU; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
 
  
 0.857
hutI
Imidazolonepropionase HutI; Belongs to the metallo-dependent hydrolases superfamily. HutI family.
 
  
 0.811
yegQ
Peptidase U32 family YegQ.
     
 0.756
hutH
Histidine ammonia-lyase HutH; Belongs to the PAL/histidase family.
 
  
 0.649
SO_3165
Toxin-antitoxin system antidote Mnt family.
       0.518
SO_3166
Toxin-antitoxin system toxin HepN family.
       0.518
prpB
2-methylisocitrate lyase PrpB; Involved in the catabolism of short chain fatty acids (SCFA) via the 2-methylcitrate cycle I (propionate degradation route). Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2- methylisocitrate to yield pyruvate and succinate via an alpha-carboxy- carbanion intermediate.
      
 0.478
puuR
Putrescine degradation gene regulator PuuR.
  
     0.431
SO_3501
Protein of unknown function DUF861.
  
    0.431
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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