| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| rfaH | rplF | SO_3194 | SO_0246 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.948 |
| rfaH | rplK | SO_3194 | SO_0220 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 50S ribosomal protein L11 RplK; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.959 |
| rfaH | rplN | SO_3194 | SO_0241 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 50S ribosomal protein L14 RplN; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.945 |
| rfaH | rpoB | SO_3194 | SO_0224 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | DNA-directed RNA polymerase beta subunit RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.949 |
| rfaH | rpsC | SO_3194 | SO_0237 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 30S ribosomal protein S3 RpsC; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.946 |
| rfaH | rpsG | SO_3194 | SO_0227 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 30S ribosomal protein S7 RpsG; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.944 |
| rfaH | rpsH | SO_3194 | SO_0245 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 30S ribosomal protein S8 RpsH; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.947 |
| rfaH | rpsS | SO_3194 | SO_0235 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 30S ribosomal protein S19 RpsS; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.944 |
| rfaH | secE | SO_3194 | SO_0218 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.952 |
| rfaH | uppS | SO_3194 | SO_1633 | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | Undecaprenyl diphosphate synthase UppS; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.962 |
| rplF | rfaH | SO_0246 | SO_3194 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 0.948 |
| rplF | rplK | SO_0246 | SO_0220 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L11 RplK; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.999 |
| rplF | rplN | SO_0246 | SO_0241 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 50S ribosomal protein L14 RplN; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.999 |
| rplF | rpoB | SO_0246 | SO_0224 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | DNA-directed RNA polymerase beta subunit RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.993 |
| rplF | rpsC | SO_0246 | SO_0237 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 30S ribosomal protein S3 RpsC; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. | 0.999 |
| rplF | rpsG | SO_0246 | SO_0227 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 30S ribosomal protein S7 RpsG; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.998 |
| rplF | rpsH | SO_0246 | SO_0245 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 30S ribosomal protein S8 RpsH; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. | 0.999 |
| rplF | rpsS | SO_0246 | SO_0235 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 30S ribosomal protein S19 RpsS; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. | 0.999 |
| rplF | secE | SO_0246 | SO_0218 | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | Preprotein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.966 |
| rplK | rfaH | SO_0220 | SO_3194 | 50S ribosomal protein L11 RplK; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | Transcriptional antiterminator RfaH; Enhances distal genes transcription elongation in a specialized subset of operons that encode extracytoplasmic components. Belongs to the RfaH family. | 0.959 |