close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SO_3278RND superfamily efflux pump MFP component; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (374 aa)    
Predicted Functional Partners:
SO_3279
RND superfamily efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   0.968
macB
ABC-type macrolide export system bifunctional ATPase and permease component MacB; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.909
tolC
Global secretion system secretin TolC.
 
 0.785
SO_3484
HAE1 family efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.783
SO_4090
ABC-type efflux system secretin component.
 
 0.782
SO_4014
HAE1 family effllux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.776
aggA
Type I protein secretion system secretin component AggA.
 
 0.764
SO_1882
HAE1 family efflux pump permease component; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.753
vexA
RND-type multidrug/detergent efflux system permease component VexA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
  
   0.730
mexF
HAE1 family efflux pump permease component MexF.
  
   0.725
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.