STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mltFMembrane bound lytic transglycosylase MltF; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. In the N-terminal section; belongs to the bacterial solute- binding protein 3 family. (478 aa)    
Predicted Functional Partners:
mltD
Membrane bound lytic murein transglycosylase MltD.
 
   
 0.947
tadA
tRNA-specific adenosine deaminase TadA; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
     
 0.938
SO_2564
Membrane-bound lytic peptidoglycan transglycosylase D.
 
   
 0.882
sltY
Soluble lytic murein transglycosylase SltY.
     
 0.855
rlpA
Septal ring lipoprotein RlpA; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
     
 0.844
SO_1994
Membrane-bound lytic transglycosylase MltB_2 family.
      
 0.822
purL
Phosphoribosylformylglycinamidine synthase PurL; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
     
 0.806
SO_3132
Uncharacterized protein.
   
    0.785
mltB
Lytic murein transglycosylase B MltB.
   
  
 0.716
blaA
Class D carbapenem-hydrolyzing beta-lactamase BlaA.
      
 0.670
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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