STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
der50S ribosome assembly GTPase Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (487 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase Cmk.
  
 0.983
dnaG
DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
  
  
 0.970
gpsA
Glycerol-3-phosphate dehydrogenase (NADP+) GpsA; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
  
 0.902
rluB
23S rRNA pseudouridine2605 synthase RluB; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.841
SO_1085
RNA pseudouridylate synthase family protein; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.806
SO_0884
Protein of unknown function DUF2390.
   
    0.798
kdsB
3-deoxy-D-manno-octulosonate cytidylyltransferase KdsB; Activates KDO8N (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in the Shewanella genus. Belongs to the KdsB family.
   
  
 0.771
SO_3583
16S rRNA pseudouridine synthase RsuA family; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.748
coxA
Aa3 type cytochrome c oxidase subunit I CoxA; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B.
   
  
 0.748
rsuA
16S rRNA pseudouridine516 synthase RsuA; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.740
Your Current Organism:
Shewanella oneidensis
NCBI taxonomy Id: 211586
Other names: S. oneidensis MR-1, Shewanella oneidensis ATCC 700550, Shewanella oneidensis MR-1, Shewanella oneidensis str. MR-1, Shewanella oneidensis strain MR-1, Shewanella sp. MR-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.